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High-fat diets alter the modulatory effects of xenobiotics on cytochrome P450 activities

Cytochrome P450 monooxygenase (P450) enzymes metabolize critical endogenous chemicals and oxidize nearly all xenobiotics. Dysregulated P450 activities lead to altered capacity for drug metabolism and cellular stress. The effects of mixed exposures on P450 expression and activity are variable and elu...

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Detaylı Bibliyografya
Yayımlandı:Chem Res Toxicol
Asıl Yazarlar: Sadler, Natalie C., Webb Robertson, Bobbie-Jo M., Clauss, Therese R., Pounds, Joel G., Corley, Richard, Wright, Aaron T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075635/
https://ncbi.nlm.nih.gov/pubmed/29688711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00008
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