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High-fat diets alter the modulatory effects of xenobiotics on cytochrome P450 activities

Cytochrome P450 monooxygenase (P450) enzymes metabolize critical endogenous chemicals and oxidize nearly all xenobiotics. Dysregulated P450 activities lead to altered capacity for drug metabolism and cellular stress. The effects of mixed exposures on P450 expression and activity are variable and elu...

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Vydáno v:Chem Res Toxicol
Hlavní autoři: Sadler, Natalie C., Webb Robertson, Bobbie-Jo M., Clauss, Therese R., Pounds, Joel G., Corley, Richard, Wright, Aaron T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075635/
https://ncbi.nlm.nih.gov/pubmed/29688711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00008
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