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Current High-Throughput Approaches of Screening Modulatory Effects of Xenobiotics on Cytochrome P450 (CYP) Enzymes

Cytochrome P450 (CYP) is a critical drug-metabolizing enzyme superfamily. Modulation of CYP enzyme activities has the potential to cause drug–drug/herb interactions. Drug–drug/herb interactions can lead to serious adverse drug reactions (ADRs) or drug failures. Therefore, there is a need to examine...

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Detalhes bibliográficos
Publicado no:High Throughput
Main Authors: Ung, Yee Tze, Ong, Chin Eng, Pan, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306765/
https://ncbi.nlm.nih.gov/pubmed/30274310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ht7040029
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