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Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes

The adverse effects to humans and environment of only few chemicals are well known. Absorption, distribution, metabolism, and excretion (ADME) are the steps of pharmaco/toxicokinetics that determine the internal dose of chemicals to which the organism is exposed. Of all the xenobiotic-metabolizing e...

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書目詳細資料
發表在:Front Pharmacol
Main Authors: Raunio, Hannu, Kuusisto, Mira, Juvonen, Risto O., Pentikäinen, Olli T.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464169/
https://ncbi.nlm.nih.gov/pubmed/26124721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00123
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