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Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes

The adverse effects to humans and environment of only few chemicals are well known. Absorption, distribution, metabolism, and excretion (ADME) are the steps of pharmaco/toxicokinetics that determine the internal dose of chemicals to which the organism is exposed. Of all the xenobiotic-metabolizing e...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Raunio, Hannu, Kuusisto, Mira, Juvonen, Risto O., Pentikäinen, Olli T.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464169/
https://ncbi.nlm.nih.gov/pubmed/26124721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00123
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