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Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes

The adverse effects to humans and environment of only few chemicals are well known. Absorption, distribution, metabolism, and excretion (ADME) are the steps of pharmaco/toxicokinetics that determine the internal dose of chemicals to which the organism is exposed. Of all the xenobiotic-metabolizing e...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Autores principales: Raunio, Hannu, Kuusisto, Mira, Juvonen, Risto O., Pentikäinen, Olli T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464169/
https://ncbi.nlm.nih.gov/pubmed/26124721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00123
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