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Cytochrome P450 and Xenobiotic Receptor Humanized Mice

Most xenobiotics that enter the body are subjected to metabolism that functions primarily to facilitate their elimination. Metabolism of certain xenobiotics can also result in the production of electrophilic derivatives that can cause cell toxicity and transformation. Many xenobiotics can also activ...

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Dettagli Bibliografici
Autori principali: Gonzalez, Frank J., Yu, Ai-Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440291/
https://ncbi.nlm.nih.gov/pubmed/16402898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.pharmtox.45.120403.100007
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