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Cytochrome P450 and Xenobiotic Receptor Humanized Mice
Most xenobiotics that enter the body are subjected to metabolism that functions primarily to facilitate their elimination. Metabolism of certain xenobiotics can also result in the production of electrophilic derivatives that can cause cell toxicity and transformation. Many xenobiotics can also activ...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440291/ https://ncbi.nlm.nih.gov/pubmed/16402898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.pharmtox.45.120403.100007 |
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