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Cytochrome P450 and Xenobiotic Receptor Humanized Mice

Most xenobiotics that enter the body are subjected to metabolism that functions primarily to facilitate their elimination. Metabolism of certain xenobiotics can also result in the production of electrophilic derivatives that can cause cell toxicity and transformation. Many xenobiotics can also activ...

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Detalhes bibliográficos
Main Authors: Gonzalez, Frank J., Yu, Ai-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440291/
https://ncbi.nlm.nih.gov/pubmed/16402898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.pharmtox.45.120403.100007
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