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Cytochrome P450 and Xenobiotic Receptor Humanized Mice

Most xenobiotics that enter the body are subjected to metabolism that functions primarily to facilitate their elimination. Metabolism of certain xenobiotics can also result in the production of electrophilic derivatives that can cause cell toxicity and transformation. Many xenobiotics can also activ...

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Bibliografische gegevens
Hoofdauteurs: Gonzalez, Frank J., Yu, Ai-Ming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440291/
https://ncbi.nlm.nih.gov/pubmed/16402898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.pharmtox.45.120403.100007
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