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Cytochrome P450 and Xenobiotic Receptor Humanized Mice

Most xenobiotics that enter the body are subjected to metabolism that functions primarily to facilitate their elimination. Metabolism of certain xenobiotics can also result in the production of electrophilic derivatives that can cause cell toxicity and transformation. Many xenobiotics can also activ...

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Bibliografiske detaljer
Main Authors: Gonzalez, Frank J., Yu, Ai-Ming
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440291/
https://ncbi.nlm.nih.gov/pubmed/16402898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.pharmtox.45.120403.100007
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