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Robustness of chlorzoxazone as an in vivo measure of cytochrome P450 2E1 activity

AIMS: Chlorzoxazone is metabolized by cytochrome P450 2E1 (CYP2E1) to a single oxidized metabolite, 6-hydroxychlorzoxazone. The aim of the study was to test the robustness of chlorzoxazone as an in vivo probe of CYP2E1 activity in humans, with emphasis on investigating short-term and long-term intra...

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Autori principali: Ernstgård, Lena, Warholm, Margareta, Johanson, Gunnar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884585/
https://ncbi.nlm.nih.gov/pubmed/15255802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02132.x
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