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Robustness of chlorzoxazone as an in vivo measure of cytochrome P450 2E1 activity
AIMS: Chlorzoxazone is metabolized by cytochrome P450 2E1 (CYP2E1) to a single oxidized metabolite, 6-hydroxychlorzoxazone. The aim of the study was to test the robustness of chlorzoxazone as an in vivo probe of CYP2E1 activity in humans, with emphasis on investigating short-term and long-term intra...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1884585/ https://ncbi.nlm.nih.gov/pubmed/15255802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02132.x |
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