Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development

Cytochrome P450s are oxidative metabolic enzymes that play critical roles in the biotransformation of endogenous compounds and xenobiotics. The expression and activity of P450 enzymes varies considerably throughout human development; the deficit in our understanding of these dynamics limits our abil...

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Detaylı Bibliyografya
Yayımlandı:Drug Metab Dispos
Asıl Yazarlar: Sadler, Natalie C., Nandhikonda, Premchendar, Webb-Robertson, Bobbie-Jo, Ansong, Charles, Anderson, Lindsey N., Smith, Jordan N., Corley, Richard A., Wright, Aaron T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2016
Konular:
Special Section on Pediatric Drug Disposition and Pharmacokinetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931891/
https://ncbi.nlm.nih.gov/pubmed/27084891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.068593
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