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2-Phenethyl isothiocyanate, glutathione S-transferase M1 and T1 polymorphisms, and detoxification of volatile organic carcinogens and toxicants in tobacco smoke

Cigarette smoke contains relatively large quantities of volatile organic toxicants or carcinogens such as benzene, acrolein and crotonaldehyde. Among their detoxification products are mercapturic acids formed from glutathione conjugation, catalyzed in part by glutathione S-transferases (GST). A rand...

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Bibliografski detalji
Izdano u:Cancer Prev Res (Phila)
Glavni autori: Yuan, Jian-Min, Murphy, Sharon E., Stepanov, Irina, Wang, Renwei, Carmella, Steven G., Nelson, Heather H., Hatsukami, Dorothy, Hecht, Stephen S.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930697/
https://ncbi.nlm.nih.gov/pubmed/27099270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-16-0032
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