Clinical Trial of 2-Phenethyl Isothiocyanate as an Inhibitor of Metabolic Activation of a Tobacco-Specific Lung Carcinogen in Cigarette Smokers

2-Phenethyl isothiocyanate (PEITC), a natural product found as a conjugate in watercress and other cruciferous vegetables, is an inhibitor of the metabolic activation and lung carcinogenicity of the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in F344 rats and A/J mice. We...

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Publicado no:Cancer Prev Res (Phila)
Main Authors: Yuan, Jian-Min, Stepanov, Irina, Murphy, Sharon E., Wang, Renwei, Allen, Sharon, Jensen, Joni, Strayer, Lori, Adams-Haduch, Jennifer, Upadhyaya, Pramod, Le, Chap, Kurzer, Mindy S., Nelson, Heather H., Yu, Mimi C., Hatsukami, Dorothy, Hecht, Stephen S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854759/
https://ncbi.nlm.nih.gov/pubmed/26951845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-15-0380
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