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2-Phenethyl isothiocyanate, glutathione S-transferase M1 and T1 polymorphisms, and detoxification of volatile organic carcinogens and toxicants in tobacco smoke

Cigarette smoke contains relatively large quantities of volatile organic toxicants or carcinogens such as benzene, acrolein and crotonaldehyde. Among their detoxification products are mercapturic acids formed from glutathione conjugation, catalyzed in part by glutathione S-transferases (GST). A rand...

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Detalles Bibliográficos
Publicado en:Cancer Prev Res (Phila)
Main Authors: Yuan, Jian-Min, Murphy, Sharon E., Stepanov, Irina, Wang, Renwei, Carmella, Steven G., Nelson, Heather H., Hatsukami, Dorothy, Hecht, Stephen S.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930697/
https://ncbi.nlm.nih.gov/pubmed/27099270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-16-0032
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