Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is a leading cause of cancer mortality in the Western world and commonly treated with genotoxic chemotherapy. Stress in the endoplasmic reticulum (ER) was implicated to contribute to chemotherapeutic resistance. Hence, ER stress related protein may be of prognosti...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Ryan, Deborah, Carberry, Steven, Murphy, Áine C., Lindner, Andreas U., Fay, Joanna, Hector, Suzanne, McCawley, Niamh, Bacon, Orna, Concannon, Caoimhin G., Kay, Elaine W., McNamara, Deborah A., Prehn, Jochen H. M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930591/
https://ncbi.nlm.nih.gov/pubmed/27369741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0948-z
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