Calcineurin Interacts with PERK and Dephosphorylates Calnexin to Relieve ER Stress in Mammals and Frogs

BACKGROUND: The accumulation of misfolded proteins within the endoplasmic reticulum (ER) triggers a cellular process known as the Unfolded Protein Response (UPR). One of the earliest responses is the attenuation of protein translation. Little is known about the role that Ca(2+) mobilization plays in...

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Hlavní autoři: Bollo, Mariana, Paredes, R. Madelaine, Holstein, Deborah, Zheleznova, Nadezhda, Camacho, Patricia, Lechleiter, James D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916823/
https://ncbi.nlm.nih.gov/pubmed/20700529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011925
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