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Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

Changes in mitochondrial morphology that occur during cell cycle, differentiation, and death are tightly regulated by the balance between fusion and fission processes. Excessive fragmentation can be caused by inhibition of the fusion machinery and is a common consequence of dysfunction of the organe...

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Autores principales: Cereghetti, G. M., Stangherlin, A., de Brito, O. Martins, Chang, C. R., Blackstone, C., Bernardi, P., Scorrano, L.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572940/
https://ncbi.nlm.nih.gov/pubmed/18838687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808249105
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