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N-terminal phosphorylation of PP2A/Bβ2 regulates translocation to mitochondria, Drp1 dephosphorylation, and neuronal survival
The neuron-specific Bβ2 regulatory subunit of protein phosphatase 2A (PP2A), a product of the spinocerebellar ataxia type 12 disease gene PPP2R2B, recruits heterotrimeric PP2A to the outer mitochondrial membrane (OMM) through its N-terminal mitochondrial targeting sequence. OMM-localized PP2A/Bβ2 in...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549015/ https://ncbi.nlm.nih.gov/pubmed/22583914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2012.08631.x |
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