Reduction of protein phosphatase 2A (PP2A) complexity reveals cellular functions and dephosphorylation motifs of the PP2A/B′δ holoenzyme

Protein phosphatase 2A (PP2A) is a large enzyme family responsible for most cellular Ser/Thr dephosphorylation events. PP2A substrate specificity, localization, and regulation by second messengers rely on more than a dozen regulatory subunits (including B/R2, B′/R5, and B″/R3), which form the PP2A h...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Jong, Chian Ju, Merrill, Ronald A., Wilkerson, Emily M., Herring, Laura E., Graves, Lee M., Strack, Stefan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2020
Pynciau:
Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186168/
https://ncbi.nlm.nih.gov/pubmed/32156701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011270
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