Dopamine D2 Receptor Relies upon PPM/PP2C Protein Phosphatases to Dephosphorylate Huntingtin Protein

Striatal dopamine D2 receptor (D2R) relies upon G protein- and β-arrestin-dependent signaling pathways to convey its action on motor control and behavior. Considering that D2R activation inhibits Akt in the striatum and that huntingtin physiological functions are affected by Akt phosphorylation, we...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Marion, Sébastien, Urs, Nikhil M., Peterson, Sean M., Sotnikova, Tatyana D., Beaulieu, Jean-Martin, Gainetdinov, Raul R., Caron, Marc G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002081/
https://ncbi.nlm.nih.gov/pubmed/24619418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.544312
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados