Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is a leading cause of cancer mortality in the Western world and commonly treated with genotoxic chemotherapy. Stress in the endoplasmic reticulum (ER) was implicated to contribute to chemotherapeutic resistance. Hence, ER stress related protein may be of prognosti...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Ryan, Deborah, Carberry, Steven, Murphy, Áine C., Lindner, Andreas U., Fay, Joanna, Hector, Suzanne, McCawley, Niamh, Bacon, Orna, Concannon, Caoimhin G., Kay, Elaine W., McNamara, Deborah A., Prehn, Jochen H. M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930591/
https://ncbi.nlm.nih.gov/pubmed/27369741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0948-z
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