Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is a leading cause of cancer mortality in the Western world and commonly treated with genotoxic chemotherapy. Stress in the endoplasmic reticulum (ER) was implicated to contribute to chemotherapeutic resistance. Hence, ER stress related protein may be of prognosti...

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Publicado en:J Transl Med
Autores principales: Ryan, Deborah, Carberry, Steven, Murphy, Áine C., Lindner, Andreas U., Fay, Joanna, Hector, Suzanne, McCawley, Niamh, Bacon, Orna, Concannon, Caoimhin G., Kay, Elaine W., McNamara, Deborah A., Prehn, Jochen H. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930591/
https://ncbi.nlm.nih.gov/pubmed/27369741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0948-z
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