ER stress signaling has an activating transcription factor 6α (ATF6)-dependent “off-switch”

In response to an accumulation of unfolded proteins in the endoplasmic reticulum (ER) lumen, three ER transmembrane signaling proteins, inositol-requiring enzyme 1 (IRE1), PRKR-like ER kinase (PERK), and activating transcription factor 6α (ATF6α), are activated. These proteins initiate a signaling a...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Walter, Franziska, O'Brien, Aisling, Concannon, Caoimhín G., Düssmann, Heiko, Prehn, Jochen H. M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2018
Konular:
Cell Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254332/
https://ncbi.nlm.nih.gov/pubmed/30287689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002121
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