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ER stress signaling has an activating transcription factor 6α (ATF6)-dependent “off-switch”
In response to an accumulation of unfolded proteins in the endoplasmic reticulum (ER) lumen, three ER transmembrane signaling proteins, inositol-requiring enzyme 1 (IRE1), PRKR-like ER kinase (PERK), and activating transcription factor 6α (ATF6α), are activated. These proteins initiate a signaling a...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6254332/ https://ncbi.nlm.nih.gov/pubmed/30287689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002121 |
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