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High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer

BACKGROUND: The mainstay of treatment in rectal cancer is neoadjuvant radio chemotherapy prior to surgery, in an attempt to downstage the tumour, allowing for more complete removal during surgery. In 40 % of cases however, this neoadjuvant radio chemotherapy fails to achieve tumour regression, partl...

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Bibliografiske detaljer
Udgivet i:Radiat Oncol
Main Authors: Flanagan, L., Kehoe, J., Fay, J., Bacon, O., Lindner, A.U., Kay, E.W., Deasy, J., McNamara, D.A., Prehn, J.H.M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480907/
https://ncbi.nlm.nih.gov/pubmed/26071313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-015-0437-1
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