XIAP impairs Smac release from the mitochondria during apoptosis

X-linked inhibitor of apoptosis protein (XIAP) is a potent inhibitor of caspases 3, 7 and 9, and mitochondrial Smac (second mitochondria-derived activator of caspase) release during apoptosis inhibits the activity of XIAP. In this study we show that cytosolic XIAP also feeds back to mitochondria to...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Flanagan, L, Sebastià, J, Tuffy, L P, Spring, A, Lichawska, A, Devocelle, M, Prehn, J H M, Rehm, M
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2010
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032314/
https://ncbi.nlm.nih.gov/pubmed/21364655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.26
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk