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Real-time single cell analysis of Smac/DIABLO release during apoptosis

We examined the temporal and causal relationship between Smac/DIABLO release, cytochrome c (cyt-c) release, and caspase activation at the single cell level during apoptosis. Cells treated with the broad-spectrum caspase inhibitor z-VAD-fmk, caspase-3 (Casp-3)–deficient MCF-7 cells, as well as Bax-de...

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Detalhes bibliográficos
Main Authors: Rehm, Markus, Düßmann, Heiko, Prehn, Jochen H.M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172837/
https://ncbi.nlm.nih.gov/pubmed/12975347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200303123
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