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Small Molecule Inhibitors of Protein Arginine Methyltransferases

INTRODUCTION: Arginine methylation is an abundant posttranslational modification occurring in mammalian cells and catalyzed by protein arginine methyltransferases (PRMTs). Misregulation and aberrant expression of PRMTs are associated with various disease states, notably cancer. PRMTs are prominent t...

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Publicat a:Expert Opin Investig Drugs
Autors principals: Hu, Hao, Qian, Kun, Ho, Meng-Chiao, Zheng, Y. George
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929062/
https://ncbi.nlm.nih.gov/pubmed/26789238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2016.1144747
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