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Small Molecule Inhibitors of Protein Arginine Methyltransferases

INTRODUCTION: Arginine methylation is an abundant posttranslational modification occurring in mammalian cells and catalyzed by protein arginine methyltransferases (PRMTs). Misregulation and aberrant expression of PRMTs are associated with various disease states, notably cancer. PRMTs are prominent t...

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Bibliografske podrobnosti
izdano v:Expert Opin Investig Drugs
Main Authors: Hu, Hao, Qian, Kun, Ho, Meng-Chiao, Zheng, Y. George
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929062/
https://ncbi.nlm.nih.gov/pubmed/26789238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2016.1144747
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