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Transient Kinetics Define a Complete Kinetic Model for Protein Arginine Methyltransferase 1

Protein arginine methyltransferases (PRMTs) are the enzymes responsible for posttranslational methylation of protein arginine residues in eukaryotic cells, particularly within the histone tails. A detailed mechanistic model of PRMT-catalyzed methylation is currently lacking, but it is essential for...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Hu, Hao, Luo, Cheng, Zheng, Y. George
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207181/
https://ncbi.nlm.nih.gov/pubmed/27834681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.757625
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