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Small Molecule Inhibitors of Protein Arginine Methyltransferases
INTRODUCTION: Arginine methylation is an abundant posttranslational modification occurring in mammalian cells and catalyzed by protein arginine methyltransferases (PRMTs). Misregulation and aberrant expression of PRMTs are associated with various disease states, notably cancer. PRMTs are prominent t...
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| Publicado no: | Expert Opin Investig Drugs |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4929062/ https://ncbi.nlm.nih.gov/pubmed/26789238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2016.1144747 |
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