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Kinetic mechanism of Protein Arginine Methyltransferase 1

Protein arginine methyltransferases (PRMTs) are SAM-dependent enzymes that catalyze the mono- and di-methylation of peptidyl arginine residues. Although all PRMTs produce mono-methyl arginine (MMA), type 1 PRMTs go on to form asymmetrically dimethylated arginine (ADMA), while type 2 enzymes form sym...

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Detalhes bibliográficos
Main Authors: Obianyo, Obiamaka, Osborne, Tanesha C., Thompson, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933744/
https://ncbi.nlm.nih.gov/pubmed/18771293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800904m
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