Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models

Fragile X is the most common monogenic disorder associated with intellectual disability (ID) and autism spectrum disorders (ASD). Additionally, many patients are afflicted with executive dysfunction, ADHD, seizure disorder and sleep disturbances. Fragile X is caused by loss of FMRP expression, which...

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Detalhes bibliográficos
Publicado no:Front Behav Neurosci
Main Authors: Choi, Catherine H., Schoenfeld, Brian P., Bell, Aaron J., Hinchey, Joseph, Rosenfelt, Cory, Gertner, Michael J., Campbell, Sean R., Emerson, Danielle, Hinchey, Paul, Kollaros, Maria, Ferrick, Neal J., Chambers, Daniel B., Langer, Steven, Sust, Steven, Malik, Aatika, Terlizzi, Allison M., Liebelt, David A., Ferreiro, David, Sharma, Ali, Koenigsberg, Eric, Choi, Richard J., Louneva, Natalia, Arnold, Steven E., Featherstone, Robert E., Siegel, Steven J., Zukin, R. Suzanne, McDonald, Thomas V., Bolduc, Francois V., Jongens, Thomas A., McBride, Sean M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928101/
https://ncbi.nlm.nih.gov/pubmed/27445731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2016.00136
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