Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models

Fragile X is the most common monogenic disorder associated with intellectual disability (ID) and autism spectrum disorders (ASD). Additionally, many patients are afflicted with executive dysfunction, ADHD, seizure disorder and sleep disturbances. Fragile X is caused by loss of FMRP expression, which...

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Publicat a:Front Behav Neurosci
Autors principals: Choi, Catherine H., Schoenfeld, Brian P., Bell, Aaron J., Hinchey, Joseph, Rosenfelt, Cory, Gertner, Michael J., Campbell, Sean R., Emerson, Danielle, Hinchey, Paul, Kollaros, Maria, Ferrick, Neal J., Chambers, Daniel B., Langer, Steven, Sust, Steven, Malik, Aatika, Terlizzi, Allison M., Liebelt, David A., Ferreiro, David, Sharma, Ali, Koenigsberg, Eric, Choi, Richard J., Louneva, Natalia, Arnold, Steven E., Featherstone, Robert E., Siegel, Steven J., Zukin, R. Suzanne, McDonald, Thomas V., Bolduc, Francois V., Jongens, Thomas A., McBride, Sean M. J.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928101/
https://ncbi.nlm.nih.gov/pubmed/27445731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2016.00136
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