Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models

Fragile X is the most common monogenic disorder associated with intellectual disability (ID) and autism spectrum disorders (ASD). Additionally, many patients are afflicted with executive dysfunction, ADHD, seizure disorder and sleep disturbances. Fragile X is caused by loss of FMRP expression, which...

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Vydáno v:Front Behav Neurosci
Hlavní autoři: Choi, Catherine H., Schoenfeld, Brian P., Bell, Aaron J., Hinchey, Joseph, Rosenfelt, Cory, Gertner, Michael J., Campbell, Sean R., Emerson, Danielle, Hinchey, Paul, Kollaros, Maria, Ferrick, Neal J., Chambers, Daniel B., Langer, Steven, Sust, Steven, Malik, Aatika, Terlizzi, Allison M., Liebelt, David A., Ferreiro, David, Sharma, Ali, Koenigsberg, Eric, Choi, Richard J., Louneva, Natalia, Arnold, Steven E., Featherstone, Robert E., Siegel, Steven J., Zukin, R. Suzanne, McDonald, Thomas V., Bolduc, Francois V., Jongens, Thomas A., McBride, Sean M. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928101/
https://ncbi.nlm.nih.gov/pubmed/27445731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2016.00136
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