Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models

Fragile X is the most common monogenic disorder associated with intellectual disability (ID) and autism spectrum disorders (ASD). Additionally, many patients are afflicted with executive dysfunction, ADHD, seizure disorder and sleep disturbances. Fragile X is caused by loss of FMRP expression, which...

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Bibliographic Details
Published in:Front Behav Neurosci
Main Authors: Choi, Catherine H., Schoenfeld, Brian P., Bell, Aaron J., Hinchey, Joseph, Rosenfelt, Cory, Gertner, Michael J., Campbell, Sean R., Emerson, Danielle, Hinchey, Paul, Kollaros, Maria, Ferrick, Neal J., Chambers, Daniel B., Langer, Steven, Sust, Steven, Malik, Aatika, Terlizzi, Allison M., Liebelt, David A., Ferreiro, David, Sharma, Ali, Koenigsberg, Eric, Choi, Richard J., Louneva, Natalia, Arnold, Steven E., Featherstone, Robert E., Siegel, Steven J., Zukin, R. Suzanne, McDonald, Thomas V., Bolduc, Francois V., Jongens, Thomas A., McBride, Sean M. J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928101/
https://ncbi.nlm.nih.gov/pubmed/27445731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2016.00136
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