2-Deoxy-d-Glucose Ameliorates PKD Progression

Autosomal dominant polycystic kidney disease (ADPKD) is an important cause of ESRD for which there exists no approved therapy in the United States. Defective glucose metabolism has been identified as a feature of ADPKD, and inhibition of glycolysis using glucose analogs ameliorates aggressive PKD in...

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Foilsithe in:J Am Soc Nephrol
Main Authors: Chiaravalli, Marco, Rowe, Isaline, Mannella, Valeria, Quilici, Giacomo, Canu, Tamara, Bianchi, Veronica, Gurgone, Antonia, Antunes, Sofia, D’Adamo, Patrizia, Esposito, Antonio, Musco, Giovanna, Boletta, Alessandra
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Nephrology 2016
Ábhair:
Basic Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926967/
https://ncbi.nlm.nih.gov/pubmed/26534924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015030231
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