2-Deoxy-d-Glucose Ameliorates PKD Progression

Autosomal dominant polycystic kidney disease (ADPKD) is an important cause of ESRD for which there exists no approved therapy in the United States. Defective glucose metabolism has been identified as a feature of ADPKD, and inhibition of glycolysis using glucose analogs ameliorates aggressive PKD in...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Chiaravalli, Marco, Rowe, Isaline, Mannella, Valeria, Quilici, Giacomo, Canu, Tamara, Bianchi, Veronica, Gurgone, Antonia, Antunes, Sofia, D’Adamo, Patrizia, Esposito, Antonio, Musco, Giovanna, Boletta, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926967/
https://ncbi.nlm.nih.gov/pubmed/26534924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015030231
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