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Inhibition of yeast ribonucleotide reductase by Sml1 depends on the allosteric state of the enzyme
Sml1 is an intrinsically disordered protein inhibitor of Saccharomyces cerevisiae ribonucleotide reductase (ScRR1), but its inhibition is poorly understood. RR reduces ribonucleoside diphosphates to their deoxy forms, and balances the nucleotide pool. Multiple turnover kinetics show that Sml1 inhibi...
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| Vydáno v: | FEBS Lett |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4925217/ https://ncbi.nlm.nih.gov/pubmed/27155231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12207 |
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