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The Structural Basis for the Allosteric Regulation of Ribonucleotide Reductase
Ribonucleotide reductases (RRs) catalyze a crucial step of de novo DNA synthesis by converting ribonucleoside diphosphates to deoxyribonucleoside diphosphates. Tight control of the dNTP pool is essential for cellular homeostasis. The activity of the enzyme is tightly regulated at the S-phase by allo...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4059395/ https://ncbi.nlm.nih.gov/pubmed/23663976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-386931-9.00014-3 |
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