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The Structural Basis for the Allosteric Regulation of Ribonucleotide Reductase

Ribonucleotide reductases (RRs) catalyze a crucial step of de novo DNA synthesis by converting ribonucleoside diphosphates to deoxyribonucleoside diphosphates. Tight control of the dNTP pool is essential for cellular homeostasis. The activity of the enzyme is tightly regulated at the S-phase by allo...

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Détails bibliographiques
Auteurs principaux: Ahmad, Faiz, Dealwis, Chris G.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059395/
https://ncbi.nlm.nih.gov/pubmed/23663976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-386931-9.00014-3
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