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Inhibition of yeast ribonucleotide reductase by Sml1 depends on the allosteric state of the enzyme

Sml1 is an intrinsically disordered protein inhibitor of Saccharomyces cerevisiae ribonucleotide reductase (ScRR1), but its inhibition is poorly understood. RR reduces ribonucleoside diphosphates to their deoxy forms, and balances the nucleotide pool. Multiple turnover kinetics show that Sml1 inhibi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FEBS Lett
Egile Nagusiak: Misko, Tessianna A., Wijerathna, Sanath R., Radivoyevitch, Tomas, Berdis, Anthony J., Ahmad, Md. Faiz, Harris, Michael E., Dealwis, Chris G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4925217/
https://ncbi.nlm.nih.gov/pubmed/27155231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12207
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