Role of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide Reductase

Ribonucleotide reductases (RRs) catalyze the rate-limiting step of de novo deoxynucleotide (dNTP) synthesis. Eukaryotic RRs consist of two proteins, RR1 (α) that contains the catalytic site and RR2 (β) that houses a diferrictyrosyl radical essential for ribonucleoside diphosphate reduction. Biochemi...

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Main Authors: Ahmad, Md. Faiz, Kaushal, Prem Singh, Wan, Qun, Wijerathna, Sanath R., An, Xiuxiang, Huang, Mingxia, Dealwis, Chris Godfrey
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589814/
https://ncbi.nlm.nih.gov/pubmed/22465672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.03.014
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