Constitutive Expression of a Dominant Negative TGF-β Type II Receptor in the Posterior Left Atrium Leads to Beneficial Remodeling of Atrial Fibrillation Substrate

RATIONALE: Fibrosis is an important structural contributor to formation of atrial fibrillation (AF) substrate in heart failure (HF). TGF-β signaling is thought to be intricately involved in creation of atrial fibrosis. OBJECTIVE: We hypothesized that gene-based expression of dominant-negative type I...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Circ Res
Egile Nagusiak: Kunamalla, Aaron, Ng, Jason, Parini, Vamsi, Yoo, Shin, McGee, Kate A., Tomson, Todd T., Gordon, David, Thorp, Edward B., Lomasney, Jon, Zhang, Qiang, Shah, Sanjiv, Browne, Suzanne, Knight, Bradley P., Passman, Rod, Goldberger, Jeffrey J., Aistrup, Gary, Arora, Rishi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920729/
https://ncbi.nlm.nih.gov/pubmed/27217399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.307878
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