Constitutive Expression of a Dominant Negative TGF-β Type II Receptor in the Posterior Left Atrium Leads to Beneficial Remodeling of Atrial Fibrillation Substrate

RATIONALE: Fibrosis is an important structural contributor to formation of atrial fibrillation (AF) substrate in heart failure (HF). TGF-β signaling is thought to be intricately involved in creation of atrial fibrosis. OBJECTIVE: We hypothesized that gene-based expression of dominant-negative type I...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Circ Res
Prif Awduron: Kunamalla, Aaron, Ng, Jason, Parini, Vamsi, Yoo, Shin, McGee, Kate A., Tomson, Todd T., Gordon, David, Thorp, Edward B., Lomasney, Jon, Zhang, Qiang, Shah, Sanjiv, Browne, Suzanne, Knight, Bradley P., Passman, Rod, Goldberger, Jeffrey J., Aistrup, Gary, Arora, Rishi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920729/
https://ncbi.nlm.nih.gov/pubmed/27217399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.307878
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg