Region-specific parasympathetic nerve remodeling in the left atrium contributes to creation of a vulnerable substrate for atrial fibrillation

Atrial fibrillation (AF) is the most common heart rhythm disorder and a major cause of stroke. Unfortunately, current therapies for AF are suboptimal, largely because the molecular mechanisms underlying AF are poorly understood. Since the autonomic nervous system is thought to increase vulnerability...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Gussak, Georg, Pfenniger, Anna, Wren, Lisa, Gilani, Mehul, Zhang, Wenwei, Yoo, Shin, Johnson, David A., Burrell, Amy, Benefield, Brandon, Knight, Gabriel, Knight, Bradley P., Passman, Rod, Goldberger, Jeffrey J., Aistrup, Gary, Wasserstrom, J. Andrew, Shiferaw, Yohannes, Arora, Rishi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824299/
https://ncbi.nlm.nih.gov/pubmed/31503549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130532
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