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Region-specific parasympathetic nerve remodeling in the left atrium contributes to creation of a vulnerable substrate for atrial fibrillation

Atrial fibrillation (AF) is the most common heart rhythm disorder and a major cause of stroke. Unfortunately, current therapies for AF are suboptimal, largely because the molecular mechanisms underlying AF are poorly understood. Since the autonomic nervous system is thought to increase vulnerability...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Gussak, Georg, Pfenniger, Anna, Wren, Lisa, Gilani, Mehul, Zhang, Wenwei, Yoo, Shin, Johnson, David A., Burrell, Amy, Benefield, Brandon, Knight, Gabriel, Knight, Bradley P., Passman, Rod, Goldberger, Jeffrey J., Aistrup, Gary, Wasserstrom, J. Andrew, Shiferaw, Yohannes, Arora, Rishi
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824299/
https://ncbi.nlm.nih.gov/pubmed/31503549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130532
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