Region-specific parasympathetic nerve remodeling in the left atrium contributes to creation of a vulnerable substrate for atrial fibrillation

Atrial fibrillation (AF) is the most common heart rhythm disorder and a major cause of stroke. Unfortunately, current therapies for AF are suboptimal, largely because the molecular mechanisms underlying AF are poorly understood. Since the autonomic nervous system is thought to increase vulnerability...

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Publicado en:JCI Insight
Autores principales: Gussak, Georg, Pfenniger, Anna, Wren, Lisa, Gilani, Mehul, Zhang, Wenwei, Yoo, Shin, Johnson, David A., Burrell, Amy, Benefield, Brandon, Knight, Gabriel, Knight, Bradley P., Passman, Rod, Goldberger, Jeffrey J., Aistrup, Gary, Wasserstrom, J. Andrew, Shiferaw, Yohannes, Arora, Rishi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824299/
https://ncbi.nlm.nih.gov/pubmed/31503549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130532
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