Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers

Transcription factors have traditionally been viewed with skepticism as viable drug targets, but they offer the potential for completely novel mechanisms of action that could more effectively address the stem cell like properties, such as self-renewal and chemo-resistance, that lead to the failure o...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:EBioMedicine
Glavni autori: Illendula, Anuradha, Gilmour, Jane, Grembecka, Jolanta, Tirumala, Venkata Sesha Srimath, Boulton, Adam, Kuntimaddi, Aravinda, Schmidt, Charles, Wang, Lixin, Pulikkan, John A., Zong, Hongliang, Parlak, Mahmut, Kuscu, Cem, Pickin, Anna, Zhou, Yunpeng, Gao, Yan, Mishra, Lauren, Adli, Mazhar, Castilla, Lucio H., Rajewski, Roger A., Janes, Kevin A., Guzman, Monica L., Bonifer, Constanze, Bushweller, John H.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919611/
https://ncbi.nlm.nih.gov/pubmed/27428424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.04.032
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items