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Collaboration of MLLT1/ENL, Polycomb and ATM for transcription and genome integrity

Polycomb group (PcG) repress, whereas Trithorax group (TrxG) activate transcription for tissue development and cellular proliferation, and misregulation of these factors is often associated with cancer. ENL (MLLT1) and AF9 (MLLT3) are fusion partners of Mixed Lineage Leukemia (MLL), TrxG proteins, a...

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Detalhes bibliográficos
Publicado no:Nucleus
Main Authors: Ui, Ayako, Yasui, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916901/
https://ncbi.nlm.nih.gov/pubmed/27310306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1177681
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