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Collaboration of MLLT1/ENL, Polycomb and ATM for transcription and genome integrity

Polycomb group (PcG) repress, whereas Trithorax group (TrxG) activate transcription for tissue development and cellular proliferation, and misregulation of these factors is often associated with cancer. ENL (MLLT1) and AF9 (MLLT3) are fusion partners of Mixed Lineage Leukemia (MLL), TrxG proteins, a...

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Dades bibliogràfiques
Publicat a:Nucleus
Autors principals: Ui, Ayako, Yasui, Akira
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916901/
https://ncbi.nlm.nih.gov/pubmed/27310306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1177681
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