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Collaboration of MLLT1/ENL, Polycomb and ATM for transcription and genome integrity
Polycomb group (PcG) repress, whereas Trithorax group (TrxG) activate transcription for tissue development and cellular proliferation, and misregulation of these factors is often associated with cancer. ENL (MLLT1) and AF9 (MLLT3) are fusion partners of Mixed Lineage Leukemia (MLL), TrxG proteins, a...
Shranjeno v:
| izdano v: | Nucleus |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4916901/ https://ncbi.nlm.nih.gov/pubmed/27310306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1177681 |
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