Laddar...

The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism

Ligand-directed signal bias offers opportunities for sculpting molecular events, with the promise of better, safer therapeutics. Critical to the exploitation of signal bias is an understanding of the molecular events coupling ligand binding to intracellular signaling. Activation of class B G protein...

Full beskrivning

Sparad:

Bibliografiska uppgifter
I publikationen:	Cell
Huvudupphovsmän:	Wootten, Denise, Reynolds, Christopher A., Smith, Kevin J., Mobarec, Juan C., Koole, Cassandra, Savage, Emilia E., Pabreja, Kavita, Simms, John, Sridhar, Rohan, Furness, Sebastian G.B., Liu, Mengjie, Thompson, Philip E., Miller, Laurence J., Christopoulos, Arthur, Sexton, Patrick M.
Materialtyp:	Artigo
Språk:	Inglês
Publicerad:	Cell Press 2016
Ämnen:	Article
Länkar:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4912689/ https://ncbi.nlm.nih.gov/pubmed/27315480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.023
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!

The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism

Liknande verk