Minireview: Signal Bias, Allosterism, and Polymorphic Variation at the GLP-1R: Implications for Drug Discovery

Lignende værker

• Second Extracellular Loop of Human Glucagon-like Peptide-1 Receptor (GLP-1R) Differentially Regulates Orthosteric but Not Allosteric Agonist Binding and Function
  af: Koole, Cassandra, et al.
  Udgivet: (2012)
• Polymorphism and Ligand Dependent Changes in Human Glucagon-Like Peptide-1 Receptor (GLP-1R) Function: Allosteric Rescue of Loss of Function Mutation
  af: Koole, Cassandra, et al.
  Udgivet: (2011)
• Second Extracellular Loop of Human Glucagon-like Peptide-1 Receptor (GLP-1R) Has a Critical Role in GLP-1 Peptide Binding and Receptor Activation
  af: Koole, Cassandra, et al.
  Udgivet: (2012)
• The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism
  af: Wootten, Denise, et al.
  Udgivet: (2016)
• Allosteric Ligands of the Glucagon-Like Peptide 1 Receptor (GLP-1R) Differentially Modulate Endogenous and Exogenous Peptide Responses in a Pathway-Selective Manner: Implications for Drug Screening
  af: Koole, Cassandra, et al.
  Udgivet: (2010)