Minireview: Signal Bias, Allosterism, and Polymorphic Variation at the GLP-1R: Implications for Drug Discovery

समान संसाधन

• Second Extracellular Loop of Human Glucagon-like Peptide-1 Receptor (GLP-1R) Differentially Regulates Orthosteric but Not Allosteric Agonist Binding and Function
  द्वारा: Koole, Cassandra, और अन्य
  प्रकाशित: (2012)
• Polymorphism and Ligand Dependent Changes in Human Glucagon-Like Peptide-1 Receptor (GLP-1R) Function: Allosteric Rescue of Loss of Function Mutation
  द्वारा: Koole, Cassandra, और अन्य
  प्रकाशित: (2011)
• Second Extracellular Loop of Human Glucagon-like Peptide-1 Receptor (GLP-1R) Has a Critical Role in GLP-1 Peptide Binding and Receptor Activation
  द्वारा: Koole, Cassandra, और अन्य
  प्रकाशित: (2012)
• The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism
  द्वारा: Wootten, Denise, और अन्य
  प्रकाशित: (2016)
• Allosteric Ligands of the Glucagon-Like Peptide 1 Receptor (GLP-1R) Differentially Modulate Endogenous and Exogenous Peptide Responses in a Pathway-Selective Manner: Implications for Drug Screening
  द्वारा: Koole, Cassandra, और अन्य
  प्रकाशित: (2010)