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The mechanistic Target of Rapamycin: The grand conducTOR of metabolism and aging

Since the discovery that rapamycin, a small molecule inhibitor of the protein kinase mTOR (mechanistic Target Of Rapamycin), can extend the lifespan of model organisms including mice, interest in understanding the physiological role and molecular targets of this pathway has surged. While mTOR was al...

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Podrobná bibliografie
Vydáno v:Cell Metab
Hlavní autoři: Kennedy, Brian K., Lamming, Dudley W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910876/
https://ncbi.nlm.nih.gov/pubmed/27304501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.05.009
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