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Mechanistic target of rapamycin signaling in mouse models of accelerated aging

The mechanistic target of rapamycin (mTOR) is an essential nutrient-sensing kinase that integrates and regulates a number of fundamental cellular processes required for cell growth, cell motility, translation, metabolism, and autophagy. mTOR signaling has been implicated in the progression of many h...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Lee, Jin Young, Kennedy, Brian K, Liao, Chen-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909891/
https://ncbi.nlm.nih.gov/pubmed/30900725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glz059
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