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Subcellular Distribution and Activity of Mechanistic Target of Rapamycin in Aged Retinal Pigment Epithelium
PURPOSE. Inhibiting mechanistic target of rapamycin (mTOR) by pharmacological or genetic approaches can extend lifespan in mammals. The kinase activity of mTOR is controlled by upstream regulatory proteins and its subcellular localization. The purpose of this study was to characterize age-related al...
Enregistré dans:
| Publié dans: | Invest Ophthalmol Vis Sci |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Association for Research in Vision and Ophthalmology
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4280880/ https://ncbi.nlm.nih.gov/pubmed/25491300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14758 |
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